The synthetic antibiotic that does not evoke bacterial resistance

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🔗 via thelancet.com.

A potentially crucial study that shows synthetic antibiotics could not only be effective but could solve the bacterial resistance problem.

Highlights

We identified a compound, COE2-2hexyl, that displayed broad-spectrum antibacterial activity. This compound cured mice infected with clinical bacterial isolates derived from patients with refractory bacteremia and did not evoke bacterial resistance.

These COE features enable the construction of a spectrum of compounds with the potential for development as a new versatile therapy for an imminent global health crisis.

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